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In contrast, depending on its concentration, IAA inhibits neuroblastoma cells, gastric cancer cells, lung cancer cells and ovarian cancer cells proliferation, through different mechanisms, including activation of Toll-like receptor 4 and MAPKs signaling [133, 134]

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These are recommended by NICE for adults with BMI 35 kg/m or BMI 3034.9 kg/m with weight-related comorbidities, limited to a maximum of 2 years' treatment