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For more information: Ezekiel Emanuel, MD, PhD, and Tricia Rodriguez, PhD, MPH, can be reached at [email protected].

While this barrier protects neural tissue from toxins and pathogens, it also significantly limits the delivery of therapeutic agents to the brain

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This triagonism distinguishes it from existing therapies such as semaglutide and tirzepatide, which focus on single or dual receptor pathways

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Ropke, K