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A structured transition planwhich may include dose tapering, washout periods, or gradual titration of the new compoundhelps maintain steady progress and minimizes rebound hunger

A growing suite of pharmacological therapies are available for CKD and common comorbidities, and should be used to aggressively manage this disease and its associated risk factors

J Diabetes Res 2018:4020492

However, there was no difference in basal sensitivity to erastin2induced ferroptosis in 0 compared to + cells, and pretreatment with nutlin-3 suppressed ferroptosis equally well in both lines (Fig S2E)