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It was proposed that disulfide formation alters catalytic efficiency by affecting the dynamic movements of the N-terminal loop (Ravilious et al., 2012)

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However, the precise molecular basis for this selectivity difference remains under investigation

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The imbalance between Gly and Gln might drive an imbalance in inhibitory and excitatory neurotransmitters, which is indicated to lead to excessive neuroinflammation (137)