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The key difference lies in the severity, duration, and the underlying impairment of stomach muscle contractions, which is a defining characteristic of gastroparesis

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Metformin is the first-line glucose-lowering agent unless the patient has a moderate to severe decline in eGFR

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Functions of vitamin D in the central nervous system include regulation of neurotransmitters, neuronal differentiation, axonal growth, voltage-sensitive calcium channels, neurotrophic factors, and ROS [138], which can affect proper neuronal function