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Conversely, excessive or high-intensity training may lead to oxidative damage in spermatozoa and increase the generation of ROS, particularly if there is insufficient recuperation

Activation of D4 could also influence T rm numbers, as this receptor can regulate expression of Kruppel-like factor 2 (Sarkar et al., 2006), a transcription factor whose downregulation is essential for T rm development

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Grifola frondosa polysaccharides induce breast cancer cell apoptosis via the mitochondrial-dependent apoptotic pathway