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Trends Neurosci (2014) 37(1):3946

For chronic constipation, NICE CKS recommends macrogol as the first-line treatment for most adults, with bulk-forming agents as an alternative when appropriate

doi: 10.1016/j.bjps.2023.04.057 Humphrey CD and Lawrence AC

"Exploring the Impact of Cigarette Smoke Extracts on Vitamin B 12 : Insights into the Transformation of Methylcobalamin and Hydroxycobalamin to Cyanocobalamin through In Vitro Evaluation"

Pour que le corps puisse en produire en quantits suffisantes, il a aussi besoin de beaucoup de vitamine C 4

And of course, you still need to avoid too much exposure from sunlight