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For academic investigative sites that did not receive a waiver to use the central IRB, full board approval was obtained from the respective governing IRBs, and documentation of approval was submitted to CorEvitas, LLC, prior to the initiation of any study procedures

PMID: 32 LockauLAtkinsonSA

The injectable form (100 mg/mL) bypasses the hepatic metabolism of oral precursors (NMN, NR) for maximum bioavailability

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and the cycling rationale (JAAOS Global, 2026)

A single 100-unit syringe cannot hold this