GI-Focused Dietary and Lifestyle Modifications Dietary adjustments work synergistically with dose titration to reduce nausea and other gastrointestinal side effects
Stay well-hydrated (2.53 liters daily), eat small balanced meals every 34 hours with adequate protein, and rise slowly from sitting or lying positions
Orforglipron (Orfoglip), approved in 2025, is the newest oral GLP-1 agonist
AI for pregnancy is 4.5 g/day, and for lactation 5.0 g/day
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It works by using phages to specifically target and eliminate pathogenic bacteria while leaving beneficial gut microbes intact, potentially restoring microbial balance and reducing inflammation