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Indeed, excess sebum is one of the key factors in this condition, as it promotes the obstruction of pilosebaceous follicles and the proliferation of Cutibacterium acnes , a bacterium involved in the development of inflammatory lesions

Wimmer E, Hellen CU, Cao X (1993) Genetics of poliovirus

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As a canonical PRR, NLRP3 constitutes the structural and functional core of the inflammasome complex [45]

External validation in a multicenter dataset of 1245 type 2 diabetes patients with AKD supports the favorable outcomes