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Exposure to reactive oxygen or nitrogen species is causatively linked to the disease pathologies associated with redox imbalance

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This physiologic release pattern is the core pharmacologic property driving continued pipeline interest

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The clodronate was encapsulated in nanoparticles to achieve macrophage depletion, resulting in a remarkable 80% increase in the rate of tumor inhibition (Hao et al., 2018)

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Behavioural studies All of the animals were individually housed in an acrylic cage (10 10 13 cm) at 25 C for at least an hour before the tests to allow for acclimatisation

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