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Baseline glucose and oxygen concentrations remained stable across groups, but IGF-1 LR3 treatment significantly reduced circulating amino acids, particularly branched-chain amino acids
FDXR deficiency (OMIM #617717) FDXR (Ferredoxin Reductase) has one FAD/NAD(P)-binding domain and two NAD(P)-binding domains
doi: 10.1016/j.pneurobio.2010.07.003 25 LarsenPVrangNTang-ChristensenM
Kadowaki T, Chin R, Ozeki A, Imaoka T, Ogawa Y (2022) Safety and efficacy of tirzepatide as an add-on to single oral antihyperglycaemic medication in patients with type 2 diabetes in Japan (SURPASS J-combo): a multicentre, randomised, open-label, parallel-group, phase 3 trial