GLP-1RAs have pleiotropic effects: they improve neurogenesis, reduce apoptosis, protect neurons from oxidative stress, and reduce neuroinflammation in various neurological conditions, and it is these beneficial effects that can be used in aging-related diseases, mainly AD and PD
Knowing the facts can help you make safer and smarter health decisions
doi: 10.3389/fcdhc.2023.1293926 Received 13 September 2023 Accepted 16 November 2023 Published 08 December 2023 Volume 4 - 2023 Edited by Azra Durak-Nalbantic, Clinical Center University of Sarajevo, Bosnia and Herzegovina Reviewed by Edin Begic, Sarajevo School of Science and Technology, Bosnia and Herzegovina Updates Copyright 2023 Ferhatbegovi, Mri and Maci-Dankovi
They concluded that incretin-based medications did not correlate with an increased risk of acute pancreatitis or pancreatic cancer compared to other oral anti-diabetic agents, which remained consistent across drug classification and duration of use [29,55]
Microdosing is considered off-label use, or prescribing an approved drug for an unapproved use, which doctors are allowed to do if they deem it medically appropriate
In clinical trials investigating transdermal GLP-1 delivery systems, researchers have explored various wearing durations, including daily and weekly applications