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Alkader DAA, Asadi N, Solangi U, Singh R, Rasuli SF, Farooq MJ, Raheela FNU, Waseem R, Gilani SM, Abbas K, Ahmed M, Tanoh DB, Shah HH, Dulal A, Hussain MS, Talpur AS

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However, long-term drug treatment can lead to a series of side effects, limiting their therapeutic effectiveness

That is a preliminary signal, not an established finding

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Comorbidities commonly associated with severe weight excess in PWS include respiratory problems (pulmonary embolism, respiratory failure, pulmonary hypertension) and sleep disorders (obstructive sleep apnea), right heart dysfunction, myocardial infarction, arterial hypertension, steatohepatitis, gallstones, deep venous thromboses, and chronic leg edema