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Due to the increased metabolism during stress or exercise, there is also an increase in free radicals that lead to faster aging of the cells

The LEAD trial (liraglutide) and the SUSTAIN trial (semaglutide) demonstrated that both drugs effectively reduce body weight, glycemia and HbA1c in patients with type 2 diabetes (77, 78)

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These numbers were all significantly higher than those reported in the placebo group