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Some researchers studying metabolic parameters specifically choose to maintain at 8mg rather than escalating further, allowing for longer protocol durations with the same vial supply

For instance, Casgevy, based on the CRISPR/Cas9 gene-editing system, was the first successful attempt at disease treatment, promising a one-time treatment for a lifelong effect. However, the complexity of clinical applications and the difficulty of target selection in gene editing have led to long treatment cycles and high costs

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Sun et al., 2016b

Stress reduction, including sleep hygiene, mindfulness, and paced breathing, reduces systemic oxidative stress and improves hormonal balance