Semaglutide and liraglutide alone are also more effective than metformin at lowering the risk of developing T2D in patients with prediabetes and pre-obesity
Diabetes (2015) 64:267684
In contrast, certain other GLP-1 receptor agonists (liraglutide, semaglutide, dulaglutide) have demonstrated cardiovascular benefits in their respective outcomes trials
Key Takeaways You can stack CJC-1295 and MK-677 because they stimulate GH through independent pathwaysGHRH amplification (pulsatile) and ghrelin receptor agonism (continuous baseline elevation)
Precision Biology-Based Lifestyle Support: The FDA requires GLP drugs to have nutrition and lifestyle support
An RCT of the Baltimore Experience Corps program showed the program led to improved cognitive function, particularly for those with impaired executive function at baseline, as well as physical and social activity (Carlson, 2021