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In a Phase 1 randomized, double-blind clinical study targeting obese participants (NCT04478708), AMG133 demonstrated acceptable safety, tolerability, and significant dose-dependent weight loss
Supportive therapies when needed
The participants came from 41 countries (6 continents) via 804 clinical sites and enrolled from October 2018 to March 2021, such that well have nearly 5-year follow-up data from the early enrollees
Lipids of the sperm plasma membrane: from polyunsaturated fatty acids considered as markers of sperm function to possible scavenger therapy
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