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These challenges have led to the development of more stable analogues, improved delivery systems, and increased interest in smaller peptide fragments that retain bioactivity while minimizing these drawbacks [9]

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Neurosci 8, 350 10.3389/fncel.2014.00350 [DOI] [PMC free article] [PubMed] [Google Scholar] Campos CA, Bowen AJ, Schwartz MW, Palmiter RD, 2016