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They are prepared by licensed compounding pharmacies under pharmacist supervision and state pharmacy board oversight

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GLP-1R activation promotes -cell proliferation and anti-apoptosis through the PI3K/Akt pathway (Table 1), contributing to an increase in -cell numbers (Liu et al., 2024)

GLP-1 receptor agonists activate satiety signals in the brain within hours, but the visible scale changes that motivate long-term commitment usually emerge over weeks rather than days

Treatment of Apoe / Irs +/ mice (a mouse model of insulin resistance, metabolic syndrome, and atherosclerosis) with either lixisenatide or liraglutide decreased atherosclerotic lesion size, generated more stable plaques with fewer lesional leukocytes, and resulted in reduced necrotic cores and thicker fibrous caps (4)

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