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Conflicts of interest disclosure The author declares there is no conflict of interest to declare

doi: 10.3389/fped.2022.875877 Received 14 February 2022 Accepted 02 May 2022 Published 24 May 2022 Volume 10 - 2022 Edited by Arjan Te Pas, Leiden University, Netherlands Reviewed by Hans Van Rostenberghe, Universiti Sains Malaysia (USM), Malaysia

Patients describe it as a premium upgrade better sleep, steadier energy, and a return of vitality, especially for those navigating age-related fatigue

The trial was stopped early due to its demonstrated efficacy, suggesting semaglutide offers a new treatment approach for CKD that benefits patients across different disease stages

inability to synthesize GSH and absence of alternative GSH-independent antioxidative systems

doi: 10.1016/j.ctim.2020.102428 130