found that the Nrf2/ARE pathway can inhibit the inflammatory infiltration of macrophages in autoimmune myositis rats [231]
143 Oxidative stress ROS are byproducts of mitochondrial oxidative phosphorylation and are scavenged by antioxidant systems
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Psychiatry 130, 110915
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However, intracellular GSH at high concentrations inactivates ROS and reduces efficacy