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Parkinson, C

To obtain orthogonal proof that our inhibitors bind to the NADP + -TGR(H) forms, we evaluated their effect on thermal stability of TGR using the thermal shift assay (TSA or differential scanning fluorometry)

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Noninvasive methods for assessing IFP include intravoxel incoherent motion-diffusion weighted imaging [22], ultrasound poroelastography [23] and contrast-enhanced magnetic resonance imaging [24]

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This contrasts with many small molecules on our list: for example, Bydureon (exenatide extended-release) had U.S