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Supplementary material The Supplementary Material for this article can be found online at: References 1 AdachiS.KawamotoT.OtsukaM.TodorokiT.FukaoK

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Before manifesting classic symptoms like pernicious anemia, patients may experience a stage of inadequacy characterized by abnormal levels of biomarkers related to vitamin B12 deficiency, such as holotranscobalamin, methylmalonic acid, and homocysteine