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CJC-1295 (no DAC) is a modified GRF(1-29), a growth-hormone-releasing-hormone (GHRH) analog that binds the GHRH receptor on pituitary somatotrophs, while Ipamorelin is a selective growth-hormone-releasing peptide (GHRP) that binds the ghrelin receptor (GHS-R1a)

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4,887 participants treated with tirzepatide and 2,328 control participants were analyzed and 142 participants had at least one MACE-4 event

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AOD-9604 appears to activate the same lipolytic pathway through a mechanism distinct from the classical GH receptor, which is why it doesn't trigger those anabolic/hormonal downstream effects