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Transwell permeable supports (batch number 3412) were purchased from Corning

10.1074/jbc.M200497200 130

TGF-1/Smad Pathway Inhibition in Hepatic Stellate Cells TGF-1 drives HSC fibrogenic activation through canonical Smad2/3 phosphorylation (ALK4/5Smad2-Ser423/425

Cycle Guidelines Common Cagrilintide Research Cycle Lengths Approach Short cycle Duration 16 weeks Review Point Week 16 Notes Reaches maintenance just as titration completes Approach Standard cycle Duration 26-32 weeks Review Point Week 26 / 32 Notes Matches Phase 2 trial durations Approach Long cycle Duration 68 weeks Review Point Week 68 Notes Matches REDEFINE 1 and REDEFINE 2 endpoints Cycle length is a research planning choice, not a treatment recommendation

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Oncol Rep 2002