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10.3390/pharmaceutics13060816 [DOI] [PMC free article] [PubMed] [Google Scholar] 219.Andreadi A, et al

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Interestingly, HGF also reduces a caspase-independent ischemic neuronal cell death by preventing apoptosis-inducing factor (AIF) translocation downstream of poly(ADP-ribose)polymerase 1 (PARP1) and p53 (Niimura et al., 2006b)

Separately, orforglipron (Foundayo) - a daily oral GLP-1 receptor agonist pill from Eli Lilly - also received FDA approval in May 2026 for weight management