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GLP-1 receptor activation inhibits the activation of hepatic Kupffer cells and infiltrating macrophages, leading to decreased production of pro-inflammatory cytokines such as TNF- and IL-1, thereby attenuating hepatic inflammation (44)

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Susan Spratt, professor of medicine at Duke University School of Medicine, said the partnerships will only improve access. The question, she added, is whether the discounts will be enough to improve access to everyone who could benefit from the medications