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Cell Res (2022) 32:68790

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In the absence of MTAP, endogenous MTA cannot be salvaged into methionine, leading to the accumulation of dcSAM and MTA, both of which inhibit methylation reactions

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Managing Existing Bruises and When to Seek Help Once bruising appears, cold therapy during the first 24-48 hours reduces swelling and discoloration by constricting blood vessels and slowing inflammatory response

Primiano, A., Persichilli, S., Ferraro, P