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Key takeaway: Nausea is the most common side effect when starting GLP-1 medications, but it is typically temporary and manageable

Taking an additional dose may disrupt your sleep architecture, leave you groggy the next morning, or result in a mild overdose

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FIGURE 8 The aforementioned abnormalities at the molecular level (downregulation of the Nrf2/HO-1 axis and GPX4) and subcellular structural level (neuronal somata and mitochondrial impairment) were consistent with the GSH metabolism perturbations identified by multi-omics analyses, collectively reflecting oxidative stress-associated damage in the hippocampus during SAE

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Tracking the frequency and severity of these symptoms helps determine whether they are transient (as is typical during dose escalation) or persistent enough to warrant intervention