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Development of lyophilization cycle and effect of excipients on the stability of catalase during lyophilization

In Vitro Cell Dev Biol Plant 48:113119 Shao HB, Chu LY, Lu ZH, Kang CM (2008) Primary antioxidant free radical scavenging and redox signalling pathways in higher plant cells

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Dose-dependently improved organ coefficients (reduced liver coefficient, increased cardiac and kidney coefficients) and reduced tissue damage (cardiomyocyte degeneration, kidney glomerular/tubular damage, hepatocyte ballooning, pancreatic islet loss) in db/db mice, with 500 mg/kg treatment more effective than metformin

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