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The FDA has approved these medications for use in patients with type 2 diabetes and for weight loss in individuals meeting certain criteria, such as BMI and weight-related conditions

Glucagon, the surprising third dial, nudges the body to spend more energy and helps clear fat from the liver

The cagrilintide-retatrutide combination stays within the incretin and satiety hormone family, while tesamorelin-retatrutide combines two entirely different hormonal systems

The team found that semaglutide users experienced between a 40% and 70% reduction in alzheimers risk compared to those receiving insulin or other diabetes treatments

The authors conclude: In this real-world study where half of patients discontinued GLP-1-based treatment within a year after initiation, not losing weight was associated with worse clinical outcomes while larger reductions were associated with decreased risks

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