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In theory, if the LDLR is inhibited, the reverse transport of cholesterol is also inhibited, and less cholesterol is absorbed into the liver, thus reducing the accumulation of cholesterol in the liver

[DOI] [PubMed] [Google Scholar] 59.Zou C.Y., Sun Y., Liang J

Inhibiting the Proteolytic Activity of DPP-4 and Early Animal Studies Inactivation of GLP-1 and GIP DPP-4 is a catalytic glycoprotein which releases a dipeptide from oligopeptides by cleaving the peptides between the second and the third amino acids from the N-terminal end provided that the second amino acid is alanine or proline (25, 26)

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Final Thoughts When comparing bariatric surgery vs Ozempic or other GLP-1s, the choice comes down to individual goals