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Although modest changes in mRNA levels of redox enzymes have previously been reported in PfK13 mutant lines 20 , our proteomics data showed that enzymes involved in GSH synthesis were unaffected by K13 mutations
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The S-lens RF level was set to 60
midzonal), and zone 3 (centrilobular)
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Red-flag criteria include rapid lesion growth, marked asymmetry, ulceration or spontaneous bleeding, nodularity, color variegation, induration, fixation to underlying tissues, pain, or associated systemic symptoms, all of which warrant prompt referral and histopathological evaluation to exclude malignancy [12,14,34,35,36,37]
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