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Semaglutide already lowers blood glucose by increasing insulin release and slowing food absorption

Additionally, semaglutide is not recommended for individuals with type 1 diabetes or diabetic ketoacidosis, as it is specifically designed for managing type 2 diabetes

Bibliografia Agenzia Italiana del Farmaco, 2022 Aggiornamento della Nota 79

Its first-mover advantage, combined with strong reimbursement coverage in major developed markets, has made it the reference molecule for obesity pharmacotherapy

But when levels stay elevated, especially in the evening, fat storage is encouraged, particularly around the abdomen

Eur J Pharm Biopharm 75:2632