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Advanced Performance Protocol Frequency: 57 sessions/week with at least 1 lower-intensity day

(2019) demonstrated that noise-induced hearing loss in mice is associated with elevated proinflammatory cytokines and microglial activation in the primary AC, and that genetic knockout of TNF- or pharmacological depletion of microglia prevented the development of tinnitus-related behavioral phenotypes

This includes wound healing trials, skin rejuvenation studies, and tissue repair research across multiple organ systems (skin, lungs, liver, bone, stomach lining)

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doi: 10.1038/nri.2016.70 138 SerbuleaVUpchurchCMAhernKWBoriesGVoigtPDeWeeseDEet al

Subsequently, the cells were cultured for additional 4 h with: i) complete DMEM