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Mechanism of the Molecular Circadian Clock The mechanism underlying cellular circadian clocks arises from an a transcriptional-translational autoregulatory feedback loop from a distinct set of genes including the Circadian Locomotor Output Cycles Kaput ( Clock ), Brain and Muscle ARNT-like Protein 1 ( Bmal1 ), Period ( Per ), and Cytochrome ( Cry )

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In male patients with androgenic alopecia, topical valproic acid spray applied twice daily for 24 weeks significantly increased total hair count compared to placebo

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