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To view or add a comment, sign in I appreciated the opportunity to be interviewed by Nick Paul Taylor for this BioSpace article discussing the FDAs recently published draft guidance, General Considerations for the Use of New Approach Methodologies in Drug Development. Historically, drug developers have often included in vitro NAM assay reports in regulatory submissions with limited explanatory context, resulting in minimal impact on the regulators safety assessment

The bottom line is that both medications have benefits and drawbacks, and your healthcare provider will help you find the one that works best for you

Some people even do daily sub-milligram doses during the initial titration phase

11 These short term effects suggest that cinnamon can alter gut hormone dynamics, though the long term impact on weight and GLP-1 biology is not established

Davies, L.F

Emergence of the obesity epidemic: 6-decade visualization with humanoid avatars