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Rutin (1.6% in HPL) has been shown to reverse hyperglycaemia-induced renal endothelial dysfunction by reducing RhoA/ROCK activation and to prevent oxidative stress by mediating Nrf2 activation (Wang et al., 2016)

352 Subsequently, PC14586 was identified through the same approach

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Increased mitochondrial calcium uniporter in adipocytes underlies mitochondrial alterations associated with insulin resistance

Differences in vasomotor responses between main stem and smaller branches of the human uterine artery