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Recent studies reveal that both gut and vaginal microbial communities directly influence hormonal regulation, immune function, and implantation success through complex interconnected pathways
Concurrently, the accumulation of peroxidation products activates the Ras/Raf/MEK/ERK pathway in endometrial cells, upregulating matrix metalloproteinase (MMP-2/MMP-9) expression and causing excessive degradation of the extracellular matrix (ECM)
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