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ELISA and western blotting analysis For ELISA, skin tissue samples of the KO and control groups were obtained and homogenized by hand grinders, removing the supernatant after centrifugation

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Gene knockout of insulin-regulated aminopeptidase: loss of the specific binding site for angiotensin IV and age-related deficit in spatial memory

A protocol planned interim analysis was conducted for this cross-over study when 12 participants completed the first administration period (period 1), in order to re-assess the sample size based on the primary outcome data

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conducted a study using cytokine-treated tissue-engineered cartilage as an in vitro model of OA to perform transcriptomic analysis