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Nguyen et al., 2018)

IV hydration therapy is a wellness service and may not be appropriate for every individual

260 Furthermore, glucagon-stimulated upregulation of H19 via the AMP/PKA pathway induces nuclear translocation of HNF4A and activates the transcription of G6PC and PCK that are involved in gluconeogenesis, resulting in hepatic glucose production

A further, similar study examining the effects of SGLT2 inhibition in combination with the loop diuretic furosemide on diuresis, with the hypothesis that SGLT2 inhibition may augment the effects of loop diuretics, is ongoing [107]