surpass cvot tirzepatide results In patients with type 2 diabetes and atherosclerotic cardiovascular disease, was noninferior to dulaglutide with respect to major cardiovascular events. Full SURPASS-CVOT trial results: https://nej.md/4qd5rLx SURPASS-CVOT — Leicester Diabetes Centre

Curr Oncol Rep 2(1):64-70, 2000

Medical Contraindications to Discuss First GLP-1 medications carry a boxed warning regarding thyroid C-cell tumors in rodent models, and the FDA mandates that patients with a personal or family history of medullary thyroid carcinoma or MEN2 do not use these drugs [3]

However, recent data also suggest that astrocytes may be involved in systemic energy balance control

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These could indicate more serious conditions that, although rare, require prompt evaluation