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A clear example of using light scattering to define a protein as disordered prior to the modern understanding of IDPs is given by 1995 study of prothymosin by Gast et al

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Metformin was also demonstrated to alter mitochondrial function in CRC, specifically increasing mitochondrial mass in SW837 cells and altering ROS production and mitochondrial membrane potential in SW837 and HCT116 cells, supporting previous studies in models of prostate, endometrial, pancreatic, lung, breast and CRC (5054)

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