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Glycine has similar effects (27,28)
Dig Liver Dis Off J Ital Soc Gastroenterol Ital Assoc Study Liver 55:2128
Thirdly, advance the development of novel saponin formulations (e.g., nanoparticle-encapsulated, receptor-targeted liposomes, pH-responsive prodrugs) and initiate phase I/II clinical trials combining these optimized formulations with standard chemotherapeutic regimens, focusing on evaluating their in vivo bioavailability, safety profiles (especially hemolytic toxicity and organ tolerance), and clinical efficacy in cancer patients, while establishing unified evaluation criteria for the therapeutic potential of saponin-based combination therapies
Blood pressure Both REDEFINE 1 and 2 reported reductions in systolic blood pressure
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