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Loss of lean muscle mass has been noted in up to 25% of patients undergoing rapid weight loss

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Based on the results obtained in the wet lab and in silico, they hypothesized that VIT-E inhibits LPx by reducing ROS and by increasing enzymatic antioxidant defense through binding of KEAP1, thus interfering with the NRF2-KEAP1 proteinprotein interaction and leading to ARE activation

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