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The benzyl preservative preservative inhibits microbial growth, allowing a single vial to be punctured multiple times over a 28-day window when stored at 28C

It also gives researchers an alternative for study designs in which injections may be unsuitable

This is the same pathway that semaglutide and the GLP-1 component of tirzepatide target

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Warnings and Precautions 5.1 Risk of Thyroid C-Cell Tumors In both sexes of rats, tirzepatide caused a dose-dependent and treatment-duration-dependent increase in the incidence of thyroid C-cell tumors (adenomas and carcinomas) in a 2-year study at clinically relevant plasma exposures [see Nonclinical Toxicology (13.1)]