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Conclusion In this real-world efficacy study, we find significant estimated treatment differences in weight loss and HbA1c reduction between patients taking GLP-1s for 12 months as compared to propensity-score matched controls followed for a similar period of time

NICE guidelines recommend achieving an HbA1c level below 48 mmol/mol (6.5%) before discontinuing contraception, provided this can be accomplished without problematic hypoglycaemia

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