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One of the reasons is that their symptoms appear to be significantly intertwined, causing difficulty in diagnosing a patient with one condition or the other

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An HNF1alpha truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonizing HNF1beta function

For gastrointestinal side effects , including nausea and reflux-related throat symptoms: Eat smaller, more frequent meals rather than large portions, which can exacerbate nausea and slow gastric emptying Avoid lying down immediately after eating

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And for understandable reasons, the drug industry isnt keen to fund studies that show disappointing results