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Once the tumour became arrested in the palbociclib-treated group, mice were further randomized to receive either RSL3 (50 mg kg 1 , five times per week for 2 weeks) or the vehicle, resulting in four experimental groups: vehicle, RSL3, palbociclib and palbociclib + RSL3

The primary victims of this relentless oxidative stress are the mitochondria, the microscopic powerhouses responsible for generating ATP

They are not intended for human consumption, diagnostic, or therapeutic use

Recently, a potent inhibitor of SLC1A5, V-9302, has been reported to be effective in several cancer cell lines and in vivo tumor models 205

Perillo, B

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